I’m a French and Portuguese molecular biologist, and I have been studying skeletal muscle for more than a decade, from development and normal physiology to how muscle is affected by disease. I am the Principal Investigator of the Matthieu Dos Santos Lab at Washington University in St. Louis (WashU), which officially launched on September 1, 2026. Our lab combines single-nucleus sequencing, genetics, comparative genomics, physiology, and mouse models to understand how muscle works and what drives its adaptations.
I completed my PhD in Paris, focusing on skeletal muscle transcription and the regulation of muscle gene expression. In 2024, I was awarded an NIH K99/R00 Pathway to Independence grant.
We are currently recruiting PhD students and postdoctoral fellows. If you are interested in studying extraordinary genetic and physiological adaptations of skeletal muscle across species, please contact Matthieu Dos Santos at matthieu.dossantos@wustl.edu.